Friday, July 18, 2008

More on Motrin and Stevens-Johnson syndrome - Los Angeles Times


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More on Motrin and Stevens-Johnson syndrome
Los Angeles Times - 12 hours ago
Unlike ear infections or strep throat or chicken pox, Stevens-Johnson syndrome isn't one of those conditions that most parents worry about.
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A consistently increasing number of people spend hundreds or even thousands of dollars every year on weight loss supplements hoping to boost their metabolism in the pursuit of achieving an higher level of attractiveness. The fitness industry is booming, but the majority of people are unable to shed those unwanted pounds in spite of all the efforts they put into exercise and dieting.

In the United States, more than sixty percent of adults are overweight and thirty percent are considered obese. Here in the U.S. we have become sedentary and have grown accustomed to an overabundance of food. We have grown dependent on convenience, which has led us to consume excess amounts of unhealthy fast foods and quick, easy to prepare meals that that aren't as healthy as they should be. We have sacrificed the healthy, home-cooked meals of the past to cater to our around-the-clock lifestyles. As a result, we're always on the lookout for a super duper weight loss miracle pill that will allow us to eat whatever we want, never exercise, and still maintain the figure of a supermodel.

Many products in the weight loss market try to sell us this so-called miracle pill using promises of unrealistic results and miracle transformations. The weight loss companies rely on the overweight person's failure to achieve the desired results and turn to the supplements as a last ditch effort to get there.

A major problem with these is that much of the information available in the market is written by the companies trying to sell the supplements. The claims are hyped-up to unrealistic levels just to make the sale. This mis-information can lead to serious health problems for people who take these supplements.

One of the major ones that has been known to cause serious problems in some dieters is ephedra. Ephedra, also known as ma huang has been used in traditional Chinese medicine for 5,000 years as a treatment for asthma, hay fever, and the common cold. Ephedra is both a stimulant (drug that temporarily increase alertness and awareness) and a thermogenic (dietary supplement used to stimulate the body's burning of fat). Ephedra stimulates the brain, increase heart rate, constricts blood vessels (increasing blood pressure), and expands bronchial tubes (making breathing easier). Ephedra's thermogenic properties cause an increase in metabolism, which is shown by an increase in body heat.

Ephedra has also been used for weight loss, sometimes in combination with aspirin and caffeine. Some studies have shown that ephedra, when taken in a regulated and supervised environment, is effective for marginal short-term weight loss, although it is unclear whether such weight loss is maintained. Side effects of ephedra may include severe skin reactions, irritability, nervousness, dizziness, trembling, headache, insomnia, profuse perspiration, dehydration, itchy scalp and skin, vomiting, hyperthermia, irregular heartbeat, seizures, heart attack, stroke, or death.

The safety of ephedra-containing dietary ones was questioned as a result of a high rate of serious side effects and ephedra-related deaths. In response to accumulating evidence of adverse effects and deaths related to ephedra, the FDA banned the sale of ephedra-containing supplements in April of 2004 and the sale of ephedra-containing dietary one is still illegal in the United States.

Although the Food and Drug Administration has managed to successfully ban the majority of illegal marketers, some unsafe products are still available. Consumers are being deceived everyday by some labels on products that claim to be ephedra free when in actuality these supplements contain other ingredients that may pose the same health risks. Be wary.

Another popular one is Epigallocatechin gallate, better known as EGCG which is a found in green tea. Although most commonly known as a powerful antioxidant and for its potential to lower cancer risk by protectingcells from the harmful effects of free radicals. Free radicals are associated with the development of diseases such as cancer, advanced aging and heart disease. Studies suggest EGCG may also help with weight loss and fat burning by promoting and stimulating thermogenesis - the burning of fat cells. Thermogenesis also results in more energy and improved endurance. EGCG may help you lose fat by stimulating fat oxidation, burning calories, suppressing cravings, and boosting energy levels.

Another popular claim of some weight loss products is that they contain ingredients to prevent the absorption of carbohydrates. A popular example of this is Chitosan. Chitosan is usually sold as a pill that claims to be a 'fat attractor'. The claim is that the pill has the capability of attracting fat from the digestive system and expelling it from the body so that users can lose weight without changing their eating habits.

Some scientific research suggests that these claims are are hard to prove. Results show that at best, unmodified chitosan would remove only about 30 calories a day from a person's diet. Modified chitosan is supposed to be able to absorb three to six times its weight in fat and oils. This is unproven and opponents claim that using chitosan may have the actually negate the effectiveness of certain minerals found in food that are required by the body in order to remain healthy.

Some products claim to make you feel more full and therefore you eat less. One of the popular supplements of this type is Guar Gum. Guar gum is a fiber that acts as a bulk forming laxative that is said to be effective in promoting regular bowel movements and relieving constipation and chronic related functional bowel ailments.

For weight loss purposes, Guar gum is a thermogenic substance. Its low digestibility makes it great for use in recipes as a filler, which can help to promote the feeling of fullness, or slow the digestion of a meal, which lowers the glycemic index of that meal. In the late 1980s, guar gum was used and heavily promoted in several weight loss products. The FDA recalled these products due to reports of esophageal blockage from insufficient fluid intake. For this reason, guar gum is no longer approved for use in over-the-counters in the U.S. Additionally, several studies found that guar gum supplements were not effective in reducing body weight.

Some of the latest innovations in the weight loss industry are creams, gels, lotions and patches; basically things that aid in weight loss by way of skin absorption. Many of these products have not been proven or disproved to be effective; there have been studies showing both positive and negative results. One popular product is Cutting Gel, which is a top-selling fat loss cream. Claims are that you rub it on the spots where you want the fat to vanish. I have seen claims that it works and claims that it doesn't.

Equally as popular are herbal patches. These patches are said to be buy bulk l ornithine a-ketogluratate okg convenient, comfortable, and effective for taking natural health supplements without taking pills or liquids orally. These products allow nutrients to be absorbed through the skin. Some of these patches, such as the Hoodia Skin Patch claims to work as a continual appetite suppressant by releasing natural Hoodia Gordonii extract via a patch placed on the body that is said to work for 24 hours. It's not clear whether these diet patches have undergone extensive scientific clinical trials or testing and therefore it can't be shown that a hoodia patch is more effective than hoodia capsules, tablets, or liquids.

Overall, it seems that the best method for losing weight is the good old fashioned way: eat healthy and stay active. Maybe instead of investing in diet supplements, invest in a good pair of walking shoes, go for a walk, do brisk walking, go jogging, hop on the treadmill, go to the gym, and most-importantly maintain well-balanced diet.

Denise Villani an author and the webmaster of several article directories. Find more articles and information on weight loss by visiting WeightLossStuff.info

Alzheimer's vaccine stopped plaque, not dementia (AP)

AP - Some doctors have long suspected that if the plaque that buy bulk mannitol nutritional powder up in the brains of patients with Alzheimer's disease could be removed, they could be saved. But a new vaccine that did just that suggests the theory is wrong.

Sutherlandia is an adaptogenic, nitrogen fixing legume with immune boosting, cancer fighting and anxiety lowering properties. With all these qualities, there is little wonder why that in the past and in modern times it is regarded as a tried and tested African herbal remedy.

Sutherlandias immune boosting properties have prompted a great deal of research especially in the context of cancer and HIV/AIDS in South Africa. Sutherlandia is traditionally named Kankerbos (Cancer Bush) by the Afrikaans nation, and inWele (hair) by the Zulu nation. This unusual name derives from the idea that the medicine would literally pick a person up by the hair, and set them on their feet again. Sutherlandia has enjoyed a good history in the field of traditional medicine. It has been used traditionally for a variety of ailments including stomach aches, internal cancers, colds, influenza to name a few . The plant presents as a small, soft wooded shrub that can grow up one meter in height. The leaflets are grey-green in colour, giving the bush a silvery appearance" . The leaves are very bitter tasting, however we have noticed that with time, one actually gets used to the taste.

Sutherlandia is relatively easily grown in your garden making it an accessible herb for those of you who enjoy making your own herbal concoctions. Dosing yourself with Sutherlandia is also relatively easy, usage is suggested as follows: "Half a bunch (10g = 3 tablespoonfuls) of dried ground herb is infused until cold with one liter of boiling water, then strained and taken in half teacupful doses (90ml) three times daily. Children 6 12 years: one quarter teacupful (45ml)" . The herb can also be dried and crushed and added to food for horses, dogs or even sheep. It is usually taken as a bitter tonic.

In modern times, research has provided a great deal of information about Sutherlandia. Much in the same way that the herb is able to adapt to harsh dry conditions, it also assists the human body in adapting to difficult times. Sutherlandia has been identified as an adaptogen, a term coined by Russian Scientist Dr. Nicolai Lazarev, referring to a natural herb that increases the body's resistance to stresses such as trauma, anxiety and bodily fatigue . In other words Sutherlandia assists the body in adapting to and fighting off invaders, a crucial quality especially in the context of HIV. Sutherlandia functions as a superb chemical factory producing a number of health enhancing compounds, these include L-canavanine, pinitol, GABA, asparagines and a novel triterpenoid glucoside known as SU1.The published biological activities of these compounds appear to validate some of the traditional uses of the plant, and further support the use of the plant as a quality-of-life tonic in cancer and AIDS patients .

Important chemical constituents of Sutherlandia:

L-Canavanine is known to occur in high levels in certain seeds. What is unusual is that significant levels of this compound are found in Sutherlandia leaves. This potent non-protein amino acid is an L-arginine antagonist with documented antiviral, anti-bacterial, antifungal and anticancer activities.

Pinitol, a known anti-diabetic agent, has been isolated from Sutherlandia leaves, and quantitative work is in progress. A US Patent suggests that pinitol may have clinical application in treating the wasting in cancer and AIDS patients.

GABA was isolated from dry Sutherlandia leaves in levels up to 14 mg/g dry weight. This inhibitory neurotransmitter could account for the use of the plant for anxiety and stress, and for the improvement in mood and well-being experienced by many patients.

Sutherlandia is an excellent adaptogenic tonic which dramatically improves the quality of life of patients with full-blown AIDS. The plant gives a sense of well-being, energy and vitality to all users, including cancer patients. It also has direct anti-cancer and anti-viral activity. It should be noted that Sutherlandia should not be used in conjuction with any anti-retrovital therapy .

As always, one can never over emphsize the importance of addressing your health holistically, if you are going to use Sutherlandia as an immune booster or for other reasons, take a few life changing steps along the way:

Address the things in your life that "get you down". When a person suffers from depression and stress, the body is flooded with a pool of immune suppressing chemicals, negative emotions affect our bodies negatively

Lower your in intake of sugar, processed and fried foods

Use a good vitamin supplement

Increase your intake of water

Increase your intake of fruit and vegetables, organic is best (especially if you have grown them in your own garden! In fact gardening is widely regarded as an immune boosting activity)

Ensure you get adequate exercise.

Clinically proven Sutherlandia products are available and can be found at: www.fevertree.za.com.

References:

1. Van Wyk, B-E., Gericke, N.P.and van Oudtshoorn, B. (1997). Medicinal plants of South Africa. Briza Publications, Pretoria.

2. http://www.plantzafrica.com/frames/plantsfram.htm

3. http://www.sahealthinfo.org/traditionalmeds/monographs/sutherlandia.htm

4. http://en.wikipedia.org/wiki/Adaptogen

5. Information Courtesy of Robert Picton - Imbizo Technologies

6. Empowerment concepts David Patient & Neil Orr

Disclaimer:

The content provided is not intended to be a substitute for qualified medical advice

Jason Mordecai is an educator and researcher with interests in Neurolinguistic Programming, Psychoneuroimmunology, herbalsim and entrepreneurism in Africa. He currently runs an innovative business that sources and supplies raw materials and products focusing on African Medicinal herbs. For more information see his website http://www.fevertree.za.com